If we had to summarize our current state of affairs in regards to CBD, we’d say it’s a most promising substance. However, it requires years of research before its potential health benefits can be fully explored.
We have compiled here some of the more frequent questions concerning CBD and its ability to treat various ailments. Research is only now picking pace, largely because of the long ban on CBD use. As a result, it may be years before medication aiming at specific diseases is available over the counter. In the meantime, most evidence is anecdotal or based on problematic research–with few participants or conducted on animals.
If you are thinking of trying CBD and are taking other medications, it’s important to consult with a doctor first. CBD could have negative interactions with other drugs or conditions. Having said that, millions of people have used CBD to improve their life throughout the centuries. And the World Health Organization (WHO) has concluded that:
“CBD is generally well tolerated with a good safety profile… To date, there is no evidence of recreational use of CBD or any public health-related problems associated with the use of pure CBD.”
- Can cannabis oil help me with my tremors?
- What health benefits does a daily CBD oil regimen have?
- What type of diseases are removed by medical marijuana?
- How to use CBD oil to control cancer pain
- Which is better for killing cancer, THC or CBD?
- Does CBD oil help diabetes?
- What happens if you overdose on CBD oil?
- What will happen if I smoke weed and use CBD oil together?
- What is the best medicine for pain: CBD oil or tincture?
- Which is better, black seed oil or CBD gold?
- Which pure CBD oil is best? Does it really work?
- What are the negative side effects of CBD oil?
- What drugs should not be combined with CBD?
- Does CBD oil work for pain?
- Is it OK to apply CBD cream to treat skin inflammation?
- Does CBD oil help anxiety?
- Can CBD treat symptoms of depression?
- Can I take CBD oil with antidepressants?
- Is THC or CBD better for treating depression?
- Is CBD oil safe for kids under 5?
- Has anyone tried using CBD oil?
- How long does it take to be weaned off CBD oil medication?
1. CAN CANNABIS OIL HELP ME WITH MY TREMORS?
Probably. Research has shown that CBD is effective in reducing inflammation and alleviating pain (European Journal of Pain, 2015). Its potent anti-inflammatory and relaxing qualities have led people to use it to alleviate symptoms from diseases such as Parkinson’s and epilepsy.
Research into the effects of CBD oil to tremors has shown that CBD works with our endocannabinoid system to control our muscles. This suggests that CBD oil can help with relaxation, while also decreasing inflammation. The result would be fewer tremors.
Given the promising results and the increasing evidence that CBD oil could be useful in alleviating tremors, there is ongoing research in this area.
2. WHAT HEALTH BENEFITS DOES A DAILY CBD OIL REGIMEN HAVE?
CBD oil has been researched for its potent anti-inflammatory and relaxing qualities, making it a good treatment for inflammatory diseases such as arthritis and multiple sclerosis. CBD oil is also believed to be effective in treating depression, insomnia, anxiety, muscle pain, tremors, acne, pain relief, and more. Within this context, CBD oil consumption could improve your quality of life with minimum side-effects.
CBD’s healing properties can be particularly beneficial to the 65+ age group. Studies indicate it can help promote bone health, improve heart health, treat diabetic complications, and reduce the neuroinflammation associated with Alzheimer’s disease.
In 2018, there were more than 75 human studies of cannabidiol which were active, recruiting volunteers or in planning stages for conditions ranging from seizures to anxiety, post-traumatic stress disorder, Crohn’s disease, heart failure, Parkinson’s disease, bipolar depression, and cocaine dependence (clinicaltrials.gov, September 2018).
3. WHAT TYPE OF DISEASES ARE REMOVED BY MEDICAL MARIJUANA?
Medical marijuana has been researched for its benefits in alleviating or curing certain diseases. However, this is still an ongoing process, and there is still no definitive answer as to its exact benefits. Please keep in mind that the FDA has not approved medical marijuana as a medicine. Unlike CBD oil, medical marijuana is obtained from cannabis and contains CBD, THC (the psychoactive compound in marijuana), and other compounds.
Medical marijuana has been used for controlling pain, especially in chronic pain cases such as pain caused by multiple sclerosis. Since medical marijuana is a muscle relaxant, it has also been used to alleviate the symptoms of Parkinson’s disease. Medical marijuana has also been useful in treating inflammation. There is ongoing research as to medical marijuana’s efficacy in decreasing tumor growth in cancer patients.
4. HOW TO USE CBD OIL TO CONTROL CANCER PAIN
CBD tinctures used to be the preferred treatment method for pain relief before the invention of aspirin, as well as the most common method of ingesting medical cannabis until it was banned in the US in 1937.
There is ongoing research on the benefits of CBD oil for pain relief in cancer patients. The initial findings are promising, since CBD oil seems to be effective in managing cancer symptoms and treatment symptoms. Due to its powerful anti-inflammatory qualities, CBD oil could act as a major pain relief by reducing inflammation. Cancer-related pain can occur either due to inflammation or tumors touching and hurting organs; CBD oil could alleviate such pain.
However, you should consult with your doctor before using cannabinoids as they can impede certain kinds of cancer treatment. You can read more about CBD and THC cannabinoids and their effect on cancer here.
5. WHICH IS BETTER FOR KILLING CANCER, THC OR CBD?
As of today, there is no FDA-approved drug protocol which includes THC or CBD for cancer treatment. Neither THC nor CBD is actively used for cancer treatment by doctors, and neither is FDA-approved for cancer treatment.
However, there has been evidence that CBD oil is effective in treating cancer-related symptoms, such as pain, and chemotherapy-related symptoms like nausea and vomiting.
THC also appears effective in treating nausea and vomiting, pain relief, and chemotherapy symptoms. However, some studies suggest it may decrease the effectiveness of certain cancer treatments.
There is plenty of ongoing research on the effects of THC and CBD in actively reducing cancer tumors, with promising initial results. A recent study (Nature, July 2018) also found that when using Chemotherapy with CBD for cancer, it inhibited the proliferation rate of cancer cells and tripled the survival rate of mice with pancreatic cancer. A 2013 study found that the combination of therapies decreased the reproduction of cancer cells, while several other studies have found that this mixture helps repair damaged cells and maintain the balance of healthy cells in the body.
If you wish to try either compound, always consult with your doctor first, as cannabinoids may interact with your treatment. Also, please bear in mind that THC is a psychoactive and hallucinogenic drug which is classified as a drug by the federal government and is legal in only 9 US states.
6. DOES CBD OIL HELP DIABETES?
There have been studies to examine the effectiveness of CBD oil on diabetes, due to its potent anti-inflammatory qualities. The initial findings are promising; there is evidence that people using CBD oil have lower insulin resistance and lower levels of blood glucose. CBD oil could reduce inflammation, pain, and blood pressure in diabetes patients as well as improve blood circulation.
In an Israel study, 68% of diabetes-prone mice who got CBD didn’t develop blood sugar problems. And CBD may represent a new agent for treating type 2 diabetes, early research suggests. However, more research is needed before a definitive claim can be made. While we’re waiting, remember that CBD oil could help you lead a better life while alleviating your symptoms from diabetes, but it does not cure diabetes and is not a replacement for your medical treatment.
7. WHAT HAPPENS IF YOU OVERDOSE ON CBD OIL?
Nothing. CBD oil does not contain any psychoactive THC. This means that you cannot overdose nor become addicted to it. The quantities required to reach an overdose level are enormous (you could also overdose on water, if you drink enough of it). Even if an individual managed to consume such large quantities of CBD oil, CBD does not act on the primary brain functions of breathing and heart beating. Therefore, even if an overdose could occur, it would not be fatal.
Also, people do not seem to build a tolerance to CBD oil. Developing a tolerance means that your body gets accustomed to the use of a substance and requires increasingly greater quantities to reach the same levels of effectiveness. However, CBD oil is not addictive and does not form a tolerance.
Indeed, studies suggest it could be used to treat addiction (Nature, March 2018). Also, CBD may, in fact, have reverse-tolerance effects (Neuroreport, 2004; Medicinal Genomics, 2011). In other words, taking CBD regularly may result in users needing less of the cannabinoid to achieve the same results.
For people with chronic pain, the best strategy is to start with a lower dosage and build up until you feel you are getting the most out of it. Getting the dosage right is crucial, as CBD may be biphasic, having one effect at a low dose and its opposite at a high one. Read more on determining the right CBD dosage for you here.
8. WHAT WILL HAPPEN IF I SMOKE WEED AND USE CBD OIL TOGETHER?
Smoking weed and taking CBD oil means you will be consuming both CBD and THC. CBD tends to reduce the effectiveness of THC, especially when it comes to its psychoactive effects. Research has shown that using THC and CBD would attenuate the least desirable effects of THC while still keeping all the beneficial ones (Front Psychiatry, 2013). So, taking CBD and THC taken together will accentuate each other’s beneficial properties.
However, research is still ongoing as to the exact ways in which these two interact. What we do know is that they both affect CB1 and CB2 receptors in our endocannabinoid system (read more on CBD, THC, and the endocannabinoid system here).
Also, remember that recreational THC is legal in only 9 US states.
9. WHAT IS THE BEST MEDICINE FOR PAIN: CBD OIL OR TINCTURE?
Both CBD oil and CBD tinctures are effective in treating pain, since they both contain CBD. However, CBD tincture is faster acting and could be more useful if you are looking for a fast pain-reliever.
CBD tinctures used to be the preferred treatment method for pain relief before the invention of aspirin. They are taken with a dropper which lets people take them sublingually (i.e., drop a few drops under the tongue). You should keep the CBD drop under your tongue for 1 or 2 minutes to let it enter your bloodstream through the mucous membrane under your tongue. This way, the tincture acts faster (as fast as 15 minutes), as it does not enter the digestive system.
CBD oil is usually added to food or taken in your drinks. If consumed as a pill or softgel, CBD oil goes through the digestive system, where it is broken down and loses a little part of its strength. It takes longer to act this way (up to two hours).
CBD oil contains hundreds of active compounds or cannabinoids. It is believed that these may be providing it with some amazing health benefits. Among its other qualities, CBD oil has strong anti-inflammatory properties and other helpful components that may help alleviate symptoms such as insomnia, arthritis, muscle pain, joint pain, low energy, depression, and anxiety.
You can read more on CBD tinctures here.
10. WHICH IS BETTER, BLACK SEED OIL OR CBD GOLD?
Black seed, also known as black cumin seed, comes from the plant, Nigella sativa and has an active ingredient called thymoquinone (TQ). Research suggests that black seed oil could help treat conditions such as cognitive diseases (Alzheimer’s), anxiety, obesity, and chronic pain thanks to TQ’s potent anti-inflammatory features. Also, studies have documented black seed oil’s antimicrobial, anti-nociceptive, and anti-epileptic properties, suggesting it could be beneficial in treating hypertension and asthma as well as metabolic syndrome and inflammatory and auto-immune disorders.
There is no FDA-approved black seed oil medication. We would advise you to consult your physician or doctor before taking it. Make sure you mention any over-the-counter medication you may be taking.
The term “CBD gold” typically refers to products with the highest and purest concentrations of CBD in the oil. This can be beneficial or problematic, depending on the specific user. Users who tolerate CBD oil well may benefit from it, while those who are sensitive to it may suffer increased adverse effects from its consumption.
11. WHICH PURE CBD OIL IS BEST? DOES IT REALLY WORK?
Millions of people around the world use CBD oil for its beneficial effects in treating chronic pain, anxiety, depression, and other illnesses. Research and studies have shown that CBD has powerful anti-inflammatory qualities, which make it ideal for treating conditions such as arthritis and muscle pain. Also, CBD oil does not contain any psychoactive compounds like THC (less than 0.3% according to the 2018 Farm Bill), which means that it is not addictive and will not make you ‘high.’
However, not all CBD oils are the same. When choosing CBD oil, make sure that:
- You select a reputable brand.
- Make sure that THC content is less than 0.3%. Check if the manufacturer offers a Certificate of Analysis (COA) which proves the content of THC in your CBD oil.
- Choose a CBD oil that has been produced from pesticide-free and heavy metals-free hemp. Farmers in several countries use hemp to soak up heavy metals and toxins from the ground. Obviously, such hemp will result in polluted CBD oil. That is why it is crucial to know where your CBD oil was produced and where the hemp flowers came from.
- Read the label carefully to know what you are buying.
- Your CBD oil is third-party tested. This means that an independent lab has verified its quality, purity, and potency.
12. WHAT ARE THE NEGATIVE SIDE-EFFECTS OF CBD OIL?
CBD oil has few side-effects as it is well absorbed by the body. However, every person is unique, and a small minority of users has experienced adverse side-effects.
Known side-effects include:
- Appetite changes: One of the benefits of CBD is that it may be able to help those with eating disorders. However, if you are taking CBD for a non-appetite-related issue, this could be an unwanted shift in your daily food intake.
- Mood changes: Studies indicate that CBD may help those with depression. So, it is not surprising that it could also cause a change in mood when you don’t want it to.
- Dizziness: Sometimes, CBD can cause a slight drop in blood pressure. This may cause you to feel dizzy or lightheaded until your blood pressure returns to normal or you get used to the slightly lower pressure.
- Drowsiness: depending on the dosage, CBD may make you feel drowsy. While this can help people suffering from insomnia, it may hinder others. It should be noted that smaller doses seem to have the opposite effect, making people more alert.
- Diarrhea: When CBD is consumed in high amounts, you may experience diarrhea. However, this does not seem to affect people who only consume normal amounts of CBD.
- Dry mouth: When used in high amounts, CBD may have an effect on your saliva production. If it decreases the function of your salivary glands, you may experience a feeling of dryness in your mouth.
- Vomiting: Some people have reported vomiting after taking CBD.
- Fast heartbeat: CBD has beneficial effects on cardiovascular risk factors and improves recovery in animal models of heart attack and stroke. However, THC can increase heart rate by 20-50 beats per minute. This increase occurs in order to compensate for the reduction in blood pressure caused by THC. Some reports find that the heart must work 30% harder in the presence of high levels of THC. So, it is important to avoid products with high THC levels.
- Nausea: CBD on its own may be able to help with nausea. However, certain products mix it with various ingredients. Some of these mixes could cause some people to feel nauseous after use.
In all cases, side-effects disappeared once users stopped using CBD.
Even though side-effects are normally minor, you should consult your doctor if you are on medication or have a preexisting condition. CBD may lower the efficiency of certain treatments and worsen the symptoms of conditions such as glaucoma, as it can increase intraocular pressure.
13. WHAT DRUGS SHOULD NOT BE COMBINED WITH CBD?
Many medically prescribed drugs are safe to take with CBD. However, some interact negatively with the Cytochrome P-450 (CYP450) system, which is found in the liver and takes care of any compounds that have the potential to be toxic by metabolizing them.
CBD can also have a similar effect on the CYP450 system, making it unable to metabolize drugs effectively. This means that there may be higher levels of certain drugs that your liver processes in your system at once, leading to negative side-effects and, theoretically (in very extreme cases), an overdose.
The drug compounds which interact with the CYP450 system include over half of any medical drugs you may use. Also, those who suffer from glaucoma should not consume CBD as it can exacerbate the ocular pressure associated with this condition.
So, and because of the possible negative interactions certain medications may have when mixed with CBD, it is important to ensure that you research the possibility and consult a doctor before you start using any CBD product. If it will cause an issue, see if the doctor can alter your current prescription dosages.
A quick list of common drug types that may be affected by CBD is shown here:
- Anti-epileptics or anti-seizure medications
- Antivirals for HIV
- Blood thinners
- Channel blockers for calcium
- Some chemotherapy drugs
- Some sedatives
A good question to ask your doctor before mixing prescribed medication and CBD is if grapefruit would interact negatively with your CYP450 system.
This is because many medications advise they shouldn’t be consumed with the fruit. Therefore, if you’re advised not to consume grapefruit while on a certain medication, the chances are the medication won’t mix well with CBD either.
Remember that more research on CBD is required in order to completely understand how it interacts with different kinds of medications. The type, quantity, purity, and quality of the CBD and medication can all cause different interactions.
If you are taking other medications, it’s important to consult with a doctor before taking CBD, as they could have negative interactions. For example, CBD can cause the levels of other medications already in your system to rise, including blood thinners such as Coumadin. And glaucoma patients should avoid CBD, as it can increase intraocular pressure.
14. DOES CBD OIL WORK FOR PAIN?
It is believed so. Indeed, CBD tinctures used to be the preferred treatment method for pain relief before the invention of aspirin.
Because of its strong anti-inflammatory and muscle relaxant properties. CBD oil has been used extensively for decades to relieve pain due to arthritis, joint pain, muscle pain, and menstrual pain.
People with arthritis, multiple sclerosis, PMS, and other chronic pain illnesses use CBD oil because of its pain-relieving qualities and few side-effects.
Also, since CBD oil is non-addictive, it is safer for use than other pain relievers.
15. IS IT OK TO APPLY CBD CREAM TO TREAT SKIN INFLAMMATION?
Generally, yes. CBD has potent anti-inflammatory and soothing qualities which can help reduce skin inflammation if applied topically.
CBD oil comes in various formats, one of which is CBD cream and gels. CBD creams can help treat eczema, skin irritations, acne, and other forms of skin inflammation. CBD creams and gels should be applied generously to the targeted area until their effects are felt.
16. DOES CBD OIL HELP ANXIETY?
It is believed so. In fact, CBD oil may be particularly suitable for treating anxiety. While there are many drugs available for treating anxiety, most of them have severe side-effects, and some become addictive.
CBD interacts with and regulates the endocannabinoid system, which plays a role in a variety of critical functions like sleep, immune responses, mood control, and more. CBD also acts on people’s serotonin levels, which are responsible for mood disorders. It can even help with recreating neurons in our hippocampus area, which is responsible for memory and cognition.
Research has shown that CBD oil can help treat anxiety disorders such as Obsessive-Compulsive Disorder (OCD), Post-Traumatic Stress Disorder (PTSD), and panic disorder (Neuropsychopharmacology, Jan 2011; Neuropsychopharmacology, May 2011).
17. CAN CBD TREAT SYMPTOMS OF DEPRESSION?
Depression has often been treated with therapy and anti-depressants. Unfortunately, these can become addictive and have severe side-effects such as sleeplessness, mood swings, and worse.
CBD oil affects the body’s internal cannabinoid system, which balances and regulates various functions in our body. Specifically, CBD interacts with serotonin—a hormone affecting our stress level. By producing more serotonin while also creating the appropriate receptors to which serotonin attaches itself, studies have found that CBD could be particularly effective in treating depression and alleviating related symptoms (CNS & Neurological Disorders, 2014; Frontiers in Immunology, 2018).
Importantly, CBD works without activating the brain’s endocannabinoid receptors directly, which indicates that it is not addictive. This is important because many people are concerned about the habit-forming potential of antidepressants. Researchers are now calling for more direct research in humans, so we should soon know more about this wonder compound.
19. CAN I TAKE CBD OIL WITH ANTIDEPRESSANTS?
CBD is a promising compound in the fight against depression. However, there is still no clear study examining the joint consumption of CBD oil and anti-depressants.
Theoretically, CBD acts on the endocannabinoid system, so CBD oil could interact with anti-depressants. Although this is a theoretical concern, there is no definitive research regarding the interaction between these two substances.
It is best to consult your doctor or physician before taking CBD oil. Mention any other over-the-counter medication you are taking so that they have a clear and accurate image of your condition and the medication you are using.
18. IS THC OR CBD BETTER FOR TREATING DEPRESSION?
Both THC (the psychoactive, hallucinogenic component of marihuana) and CBD interact with our body’s internal endocannabinoid system. This makes both potential allies in our fight against depression. However, treating depression with THC is not possible in many US states, as THC is not legal at a federal level. Some states such as Washington, Oregon, California, Nevada, Colorado, Alaska, Vermont, Massachusetts, Maine, and Michigan have legalized it, but THC is still illegal at the federal level.
That is because there is minimal evidence that THC can effectively relieve stress and anxiety, while it can cause anxiety or paranoia. Also, there is substantial evidence for increased risk for development of schizophrenia or other psychoses. And while there is emerging evidence for increased risk for depression and moderate evidence for increased suicidal thoughts, there is no evidence for decreased symptoms of depression. In short, available research indicates that THC is more likely to increase mental health problems rather than reduce them (Journal of Affective Disorders, 2018; Psychological Medicine, 2014).
CBD, on the other hand, has been found to be effective in treating depression due to CBD’s serotonin-enhancing qualities and its ability to increase the functioning of our internal cannabinoid system (Journal of Affective Disorders, 2018). By producing more serotonin while also creating the appropriate receptors to which serotonin attaches itself, studies have found that CBD could be particularly effective in treating depression and alleviating related symptoms (CNS & Neurological Disorders, 2014; Frontiers in Immunology, 2018). It should be stressed that CBD oil does not contain THC, which means it is not addictive nor hallucinogenic.
20. IS CBD OIL SAFE FOR KIDS UNDER 5?
That is unclear. What little research has been done regarding CBD oil and children has focused on children with seizures and epilepsy (Karger, 2018). This started when parents experimenting with self-medication for their children discovered that CBD had a therapeutic effect on a severe form of epilepsy in children, called Dravet syndrome. This has led to the development of Epidiolex, an FDA-approved pharmaceutical CBD product which is a medication for childhood epilepsy syndromes.
However, there are few studies examining the effects of CBD oil on children under 5, and the long-term effects of high-dose CBD on children’s brain functions remain unclear. All we know at the moment is that the endocannabinoid system is central in the proper neuronal development of the adolescent brain.
While CBD oil is legal across the US and has a lot of potential, especially in the areas of anxiety, depression, or pain, you should consult your doctor or pediatrician before administering CBD oil to your child. You should also mention to your doctor any other medication or over-the-counter medication that your child might be using.
21. HAS ANYONE TRIED USING CBD OIL?
Literally, millions of people. Despite what many people think, the possible therapeutic benefits of cannabis are not a modern-day discovery. Chinese emperors as far back as 2737 BC started using cannabis-infused teas as a method of improving memory and treating malaria.
In the West, Queen Victoria used cannabis to relieve menstrual cramps. However, cannabis began to be more intensely studied in the 1800s when a man named William B. O’Shaughnessy dived into its possible therapeutic effects. He studied the basic effects of the cannabis plant and found it may have anesthetic properties. Although his studies were controversial, several researchers began to follow in his steps, and soon, cannabinoids were discovered.
Many people across the US and throughout the world have been using CBD oil for decades to alleviate their symptoms or treat various ailments. Research indicates that CBD oil can be highly effective in treating chronic pain and inflammation, making it ideal for treating arthritis (European Journal of Pain, 2015). It has also been used to treat multiple sclerosis, muscle main, PMS and menstrual pain, anxiety, and depression. It has few side-effects, is not addictive, and is safe for use.
One of the most promising aspects of CBD lies with cancer treatment. For years, people undergoing cancer therapy have used it to alleviate symptoms such as pain and chemotherapy-related symptoms like nausea and vomiting. A recent study (Nature, July 2018) also found that combining chemotherapy with CBD inhibited the proliferation rate of cancer cells and tripled the survival rate of mice with pancreatic cancer. A 2013 study found that the combination of therapies decreased the reproduction of cancer cells, and many other studies have found that the combination actually helps repair damaged cells and maintain the balance of healthy cells in the body. You can read more about CBD and THC cannabinoids and their effect on cancer here.
As a result, the 2018 Farm Bill has approved the use of CBD across all 50 states as long as it contains less than 0.3% of THC.
Millions of people have tried CBD oil as oil, tincture, capsule or gummy and have experienced positive benefits. CBD’s healing properties can be particularly beneficial to the 65+ age group, as studies have shown that it can help promote bone health, improve heart health and treat diabetic complications, and reduce the neuroinflammation associated with Alzheimer’s disease.
22. HOW LONG DOES IT TAKE TO BE WEANED OFF CBD OIL MEDICATION?
There is no need to be weaned off CBD oil, as CBD oil is not addictive. Indeed, studies suggest it could be used to treat addiction (Nature, March 2018).
There are two kinds of CBD oil: full-spectrum, which contains under 0.3% THC, the active psychoactive and hallucinogenic substance in marijuana. And broad-spectrum CBD oil, which has no THC at all. Neither of these has been found to be addictive.